Cushing's Disease

Cushing's Disease

Cushing's disease results from an excess of adrenal gland hormones. It is a common side-effect of drugs such as corticosteroids, which are often prescribed to treat canine arthritis, allergies and other ailments. Cushing's disease can also result from a benign tumor on one of the adrenal glands or the pituitary gland.

Symptoms of Cushing's disease include:

• Increased thirst and appetite
• Frequent urination
• Loss of hair
• Skin problems
• Panting
• High blood pressure
• Increased susceptibility to infections

If left untreated, Cushing's disease can lead to other conditions like diabetes and heart problems.

Conventional Therapies

Note: Your dog's Cushing’s could be caused by a corticosteroid drug - it may be possible to wean your dog off the drug; however, this must be performed under professional supervision to avoid complications. You can speak to your vet about this. Corticosteroids sometimes have side effects that are worse than the condition they were used to treat, and make your dog more susceptible to bacterial and viral infections. Every day, we get calls from customers looking for an alternative to steroid drugs.

Antineoplastic drugs - During its evaluation as an insecticide, a leading antineoplastic drug was discovered to have adrenocorticolytic effects. The most obvious and rapid response is a reduction in water intake, urine output, and appetite, which usually occur at the end of the initial course of therapy. Muscle strength and exercise tolerance improve over the first 3-4 weeks. Skin and hair coat changes take longer and the progress is variable. After the first re-evaluation, rechecks should be scheduled every 3-6 months for the rest of the pet’s life to determine whether the dose needs to be adjusted depending on the results of ACTH response testing. Overall, based on the results of three survival studies, the mean survival time of canines with pituitary-dependent Cushing’s disease, that were treated with this drug, is 24 to 30 months with a total range of 1 day to 13 years.

Surgery - If your dog's Cushing's disease was caused by a tumor, surgery might be an option. Only your vet is qualified to consult with about this option.

3-beta-hydroxysteroid-dehydrogenase drugs - These drugs have been shown to be an effective treatment for canine and feline Cushing’s syndrome. These are a synthetic, orally active steroid analogue. They act as a competitive inhibitor of the 3β-hydroxysteroid dehydrogenate enzyme system and thereby inhibit the synthesis of cortisol and aldosterone as well as other steroids. The blockade is reversible and appears to be dose-related.

A word from our veterinarian:

It is important to note that long-term use of corticosteroid drugs (usually prescribed for inflammatory discomfort such as skin allergy or arthritis) can result in a rebound effect and excess production of cortisol by the adrenal glands can ensue. Excessive production of cortisol can also be caused by a tumor, either of the pituitary or the adrenal glands.

What is Adrenal Harmony Gold?

Adrenal Harmony Gold was developed by our holistic veterinarians to support your dog with Cushing's. The therapeutic actions of the ingredients are:  adaptogenic, antioxidant and will support the nervous system. These herbs are particularly suited to targeting the adrenal glands and its functions, but also exert an effect on the pituitary and hypothalamus glands. "Adaptogens" are a classification of herbs considered to support the adrenals, helping the body adapt naturally to stressors and produce normal, healthy levels of cortisol. Unlike drugs, adaptogens will not stimulate or depress adrenal function but, rather, help the adrenals normalize their hormone production. Antioxidants counter oxidative (free radical) damage that can lead to degeneration.

Together, the ingredients in Adrenal Harmony Gold target key cellular mechanisms to help maintain normal balance. 

What is Adrenal Harmony Gold used for?

Adrenal glands play a vital role in the health of your pet. The adrenal glands are two small glands situated on top of each kidney and they are involved in a multitude of physiological processes. The hypothalamus and pituitary glands are responsible for sending messages to the adrenals so they can secrete the right amount of hormones and maintain equilibrium within the body.

Some of the main adrenal gland functions are to:

• Help the body respond to stress and inflammation through their production of corticosteroid hormones.
• Play an important role in regulating water and electrolyte balance (affects urine output and thirst).
• Produce hormones that affect blood sugar (affects appetite).

Adrenal Harmony Gold targets the HPA (hypothalamus-pituitary-adrenal) axis to strengthen the body's internal feedback mechanisms. This in turn, can affect areas of the body influenced by the adrenal glands. Expect improved quality of life within the first two weeks of starting this formula. If you have not seen an improvement within two weeks, the dose may be safely increased. The "Directions" tab has more details.

Can my dog take Adrenal Harmony Gold with medications?

Do not give Adrenal Harmony Gold if your pet is taking blood-thinners. A veterinarian who has performed a complete medical check of your dog can help to establish safety of medications taken with other products or specific diets.

Does it come with a guarantee?

Yes!  Adrenal Harmony Gold comes with a 90-day, money-back guarantee.

Why choose Adrenal Harmony Gold for your canine friend?

• Certified organic and ethically wild-harvested:  Our formulas are entirely prepared from organically grown and ethically wild-harvested herbs.
• Good Manufacturing Practices:  All of our formulas are manufactured in a facility that adheres to Good Manufacturing Practices.
• Full Sprectrum Extract:  The full biochemical spectrum of the herbs is preserved  to ensure the potency of the extract.  All raw materials are tested for identification and purity.
• Every batch tested:  Every batch of our Adrenal Harmony Gold is tested to ensure the highest quality and potency.  Every single batch.
• FDA-Registered Facility:  Our manufacturing facility is FDA-registered.  Strict quality control procedures are meticulously monitored.
• FDA Center for Veterinary Medicine Guidelines:  PetWellbeing.com complies with the provisions of the CVM's good guidance practices for pet dietary supplements.  All ingredients and caution statements adhere to these national guidelines.
• It's Guaranteed:  In addition to the superior quality of our products, you are also protected by our 90-day moneyback guarantee.

Who makes Adrenal Harmony Gold?

Adrenal Harmony Gold is made by PetWellbeing.com, founded in 2001.  Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet.  When your pet is healthy; you're happy.

To fulfill our vision, our on-staff, holistic veterinarians have developed formulas using time-honored, traditional uses of herbs, and integrated the latest scientific research.  It is our aim to produce the best products for your pet that we can.

Healthy Tip from Dr.Jan

Advice from our on-staff veterinarian:

The liver performs dozens of different functions in the body, including clearing out toxins. Yet liver disease (including cirrhosis) is one of the most common health problems in older canines. It can damage all functions of the dog’s liver, with very harmful health effects.

Even canines without liver disease may need support to metabolize and excrete prescription medications, which are often damaging to the liver. Milk Thistle is an excellent way to support the liver in dealing with the toxic load of medications.

Milk Thistle should be administered to every dog taking liver-taxing medications and especially if the liver is damaged or diseased. Milk Thistle is not contraindicated with conventional medications and is gentle enough for long-term use.

Note: Some Milk Thistle sold in health stores is alcohol-based and should not be given to dogs. Pet Wellbeing Milk Thistle is glycerin-based and safe for dogs.

The active ingredients in Milk Thistle are known collectively as silymarins. These constituents:

• Help maintain the health of your dog’s liver
• Scavenge for harmful free radicals
• Help guard against toxins trying to bind to the dog’s liver
• Support the stability of liver membranes

As an anti-oxidant, silymarin is even more effective than vitamin E. It also helps support the production of new liver cells.

Milk Thistle provides beneficial support when your canine is being treated with:

• Anti-inflammatories:  NSAIDS and steroids
• Chemotherapy agents
• Bile acids
• Immunosuppressants
• Seizure medication
• Sulfa antibiotics
• Daily heartworm medications

Healthy Nutrition Tip for Your Dog's Liver 

Processed foods stress your dog’s liver as it attempts to detoxify the preservatives and other additives like artificial flavors and colors. Go natural! Avoid grains and focus on healthy proteins from free-range, grass-fed animals. Green foods will help detoxify your canine's liver, such as those in Pet Wellbeing's SPARK. Expect your dog’s moods to be lifted as well! SPARK is a veterinarian-formulated, daily nutritional supplement for dogs of all ages.

Remember!

Milk Thistle must be glycerin-based to be safe for dogs. Do not give your dog any supplements that contain alcohol.

Why choose Milk Thistle for your canine friend?

• Certified organic herb: Our Milk Thistle formula is prepared from organically grown herb.
• Good Manufacturing Practices: All of our formulas are manufactured in a facility that adheres to Good Manufacturing Practices.
• Full Spectrum Extract: The full biochemical spectrum of the herbs is preserved to ensure the potency of the extract. All raw materials are tested for identification and purity.
• Every batch tested: Every batch of our Milk Thistle is tested to ensure the highest quality and potency. Every single batch.
• FDA Registered Facility:  Our manufacturing facility is FDA registered. Strict quality control procedures are meticulously monitored.
• FDA Center for Veterinary Medicine Guidelines:  PetWellbeing complies with the provisions of the CVM's good guidance practices for pet dietary supplements. All ingredients and caution statements adhere to these national guidelines.
• It's Guaranteed:  In addition to the superior quality of our products, you are also protected by our 90 day money-back guarantee.

Who makes Pet Wellbeing Milk Thistle?

This product is made by PetWellbeing, founded in 2001. Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet. When your pet is healthy; you're happy.

To fulfill our vision, our on-staff, holistic veterinarians have developed formulas using time honored, traditional uses of herbs and integrated the latest scientific research. It is our aim to produce the best products for your pet that we can.

What is Pet Melatonin?

Melatonin is a naturally-occurring hormone produced in the pineal gland of dogs (and other animals), and plays a large role in regulating sleep patterns. It also has a role in the regulation of cortisol production. In dogs, melatonin supplementation has been shown to target the adrenal cells and the amount of cortisol they make. This may support normal hair growth, normal appetite and urination in dogs. It has been shown that having a consistent level of melatonin in the body can help support balanced cortisol output by the adrenal glands. Melatonin inhibits some of the enzymes needed for the body to produce more cortisol.

Pet Melatonin is different from melatonin used for human consumption. It is a unique liquid form that makes it ideal to administer to dogs of all sizes in the correct amounts, unlike capsules or tablets. It is synthetically derived and not made from the pineal glands of pigs. A synthetic melatonin ensures safety from viruses or other microbes that can be present in animal tissue. Pet Melatonin is also not a quick-release or a slow acting form of melatonin. A simple form of melatonin is the ideal way to administer this supplement to a dog, and not quick or slow release. Pet Melatonin is enhanced with natural bacon flavor so it is something your dog will enjoy.

What is Pet Melatonin used for?

Pet Melatonin is a supplement made just for dogs. Animal studies have shown promising results supplementing melatonin to animals for adrenal support. By supporting the adrenals to be balanced, with normal cortisol production, dog owners report normal hair growth, less stress, normal energy levels and normal appetite and urination in their dogs.

For dogs who experience anxiety for any reason (such as separation anxiety), melatonin is often the key to helping dogs maintain less stress in their day.

Pet Melatonin can also assist dogs if normal sleep patterns need to be achieved.

To recap, Pet Melatonin can help with:

• Normal cortisol production by the adrenal glands
• Normal hair growth
• Regular appetite and urination
• Anxiety from separation and less stress
• Anxiety due to things like loud noises
• Sleep patterns

A Note from our Veterinarian...

A primary recommendation for dogs who are taking Adrenal Harmony Gold, is to also administer Pet Melatonin. Some dogs will initially experience an increase in relaxation (decreased activity) and more sleep. This usually stabilizes within about two weeks.

As mentioned, the daily administration of Pet Melatonin (and thus a constant level in the bloodstream) is what helps to target the cells of the adrenal gland and cause more normal cortisol production.

As a third recommendation, look for a reputable supplier of lignans. The perfect combination to supporting dog adrenals is:

• #1 Adrenal Harmony Gold
• #2 Pet Melatonin
• #3 Lignans

Nutrition:

Make sure your dog receives a diet high in nutrients. A supplement like SPARK found here: http://www.petwellbeing.com/products/spark-daily-nutritional-supplement-for-dogs-and-cats-200g contains nutrients and superfoods from whole food sources, along with probiotics and enzymes for overall good health, immunity and energy.

Can my dog take Pet Melatonin with prescription drugs?

There are no studies showing drug interaction with prescription drugs. Always check with your veterinarian

Does it come with a guarantee?

Yes! Melatonin for Dogs comes with a 90 day money-back guarantee.

Why choose Pet Melatonin for your canine friend?
 

• Pure, synthetic melatonin:  No animal tissue is used to create Pet Melatonin, assuring no contamination from animal sources.
• It's a liquid:  Easy to administer the correct amount using the calibrated dropper.
• Every batch tested:  Every batch of our Pet Melatonin is tested to ensure the highest quality and purity. Every single batch.
• Certified GMP Facility:  Nationally recognized quality control procedures are meticulously monitored. Consumers can be assured that the highest standards of manufacturing are strictly adhered to.
• FDA-Registered Facility:  Our manufacturing facility is FDA-registered. Strict quality control procedures are meticulously monitored.
• FDA Center for Veterinary Medicine Guidelines:  Pet Wellbeing complies with the provisions of the CVM's good guidance practices for pet dietary supplements. All ingredients and caution statements adhere to these national guidelines.
• It's guaranteed:  In addition to the superior quality of our products, you are also protected by our 90 day money-back guarantee.
• Manufactured in the United States

Who makes Pet Melatonin for Dogs?

Pet Melatonin for Dogs is made by Pet Wellbeing, founded in 2001. Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet. When your pet is healthy; you are happy.

To fulfill our vision, our on-staff, holistic veterinarians have developed formulas using time-honored, traditional uses of herbs and integrated the latest scientific research. It is our aim to produce the best products for your pet that we can.

These statements have not been evaluated by the Food and Drug Administration. This product and information is not intended to diagnose, cure, treat, mitigate or prevent any disease or condition.

Did You Know…

Many decades ago, there was no such thing as branded pet food in the grocery aisles. Dogs ate what was available, like kitchen scraps or less expensive meat cuts and offal (organ meats) purchased at the butcher.

With significant growth in the pet industry from the mid 20th century onward, branded pet foods were sold to pet owners as optimal, even essential, diets for their family’s pets. The foods mostly contained inexpensive byproducts of human food, particularly as human foods became more and more processed. Byproducts are what is left when the main nutritional value is already used.

Today, there is a growing desire – among discerning consumers – to know more about what goes into their companions’ food.

Looking through the publication of “approved” pet food ingredients in the U.S. gives a clear indication that many ingredients are the “leftovers” after the processing of grain, plants, meat, fish, egg and dairy products.

An optimal diet is good health insurance for your canine, and can go a long way in preventing potential ailments.

What is in Premium Holistic Formula?

• Only human-grade poultry goes into Premium Holistic Formula.

No animal byproducts or “leftovers”.

• No corn or soy

• Omega-3 fatty acids from algae sources. Microalgae is the most sustainable source of EPA and DHA – it is only because fish eat microalgae that they contain Omega-3’s!

• No antibiotics or hormones. We source local meat so we know where it comes from.

• None of the ingredients are from genetically modified organisms (GMO).

• “Untainted” vitamins and minerals from trusted sources.

It Gets Better…

• No artificial preservatives.

• Protein, fat and caloric density is ideal for most dogs.

• L-Carnitine helps maintain cellular energy and cardiovascular health

• Appropriate for all life stages.

• Dog owners report less allergy symptoms when feeding a grain-free diet.

• Probiotics and prebiotics support healthy digestion.

• Quality Control: continual testing by an independent lab.

• Made in the U.S.A.

Does it come with a guarantee?

Yes! Premium Holistic Formula comes with a 30-day money-back guarantee.

A Note from Our Veterinarian:

There are many healthy diets for dogs. “Biologically-appropriate” is a term we often hear. For many years, most dog foods available were less-than-optimal when you consider that canines evolved primarily as meat-eaters.

The best diet for your dog is also one that fits the lifestyles and budget of the people who feed the dog. For example, a raw diet may be fantastic but not everyone is able to prepare or defrost the raw meat/fish. Homemade diets, though they can be excellent, may not be something you can find the extra time and energy to prepare.

Premium Holistic Formula is an excellent choice. It can be fed as the dog’s entire meal plan. It can be used to supplement or provide variety to other diets. You can also feed it as an occasional “treat” because (almost all) dogs go nuts for this food!

Who makes Premium Holistic Formula?

This pet food is brought to you by Pet Wellbeing, founded in 2001. Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet. When your pet is healthy; you're happy. Manufactured in the USA.

Why choose this product for your canine?

APHIS Inspected. Our pet food is manufactured in a facility that adheres closely to the Animal and Plant Health Inspection Service (APHIS) standards.

USDA Inspected. Our manufacturing facility is inspected by the United States Department of Agriculture (USDA). 

EU Certified. Annual inspections are part of EU (European Union) Cerification. All meat and fish must be fit for human consumption, and all ingredients must be guaranteed non-GMO.

It's guaranteed. In addition to the superior quality of our products, you are also protected by a 30-day money-back guarantee. If, for any reason, you or your canine are not completely satisfied with the product, simply return the unused portion in the package.

Our Top Three Products for Dog Cushing's

This combination:

• Promotes healthy skin and coat
• Helps normal hair growth
• Supports normal thirst and urination
• Supports healthy weight and normal appetite
• Supports proper muscle tone
• Helps with anxiety and normal sleep patterns

A comment from our veterinarian

"As a veterinarian, it is challenging to treat this condition. I have noticed remarkable differences to dogs' quality of life when these three supplements are given daily. It's so nice to have something effective to offer my patients with Cushing's."

Description

Cushing's disease is the result of excessive levels of cortisol (a steroid hormone) in your dog's body for a long period of time. Cortisol is naturally produced by the adrenal glands that sit on top of the kidneys. During times of stress, or simply when more cortisol is needed, the hypothalamus and pituitary glands signal the adrenal glands to release more of the hormone into the body. There are three types of Cushing's disease that disrupt this process, and create a harmful level of cortisol in the body.

• Pituitary dependent - Affecting the majority of dogs with the disease, a tumor develops on the pituitary gland, signalling the adrenals to overproduce cortisol.
• Adrenal dependent - Much less frequently, a tumor may develop on one of the adrenal glands, directly leading to the overproduction of cortisol.
• Iatrogenic - After chronic use of corticosteroid drugs, used to treat other illnesses, Cushing's-like signs begin to develop.

How do you know if your dog is suffering from Cushing's? The disease is not very easy to diagnose, as cortisol levels fluctuate in the body at all times. A dog with Cushing's may exhibit these signs:

• Increased thirst and appetite
• Frequent urination
• Loss of hair
• Skin problems
• Panting
• Increased susceptibility to infections

Dr. Jan's Cushing's Kit for Dogs includes Adrenal Harmony Gold, Pet Melatonin, and Milk Thistle.

Adrenal Harmony Gold

This natural, liquid supplement was developed by our holistic veterinarians to support dogs with the physical manifestations of Cushing's. The therapeutic actions of the ingredients are: adaptogenic, antioxidant, and to give support to an overactive nervous system. These herbs are particularly suited to target the adrenal glands and their functions, but also exert an effect on the pituitary and hypothalamus glands.

"Adaptogens" are a classification of herbs considered to support the adrenals, helping the body adapt naturally to stressors and produce normal, healthy levels of cortisol. Unlike drugs, adaptogens will not stimulate or depress adrenal function, but instead they will help the glands normalize their production of hormones. As antioxidants, they will also combat oxidative (free radical) damage that can lead to degeneration.

Together, the ingredients in Adrenal Harmony Gold target key cellular mechanisms to help maintain normal balance.

Pet Melatonin

Melatonin is a naturally-occurring hormone produced in the pineal gland of dogs (and other animals), and plays a large role in regulating sleep patterns. It also has a role in the regulation of cortisol production.

In dogs, melatonin supplementation has been shown to target the adrenal cells and the amount of cortisol they make. This may support normal hair growth, normal appetite, and regular urination in dogs. It has been shown that having a consistent level of melatonin in the body can help support balanced cortisol output by the adrenal glands. Melatonin inhibits some of the enzymes needed for the body to produce more cortisol.

Pet Melatonin is different from the melatonin used for human consumption. Unlike capsules or tablets, its unique liquid form makes it ideal to administer to dogs of all sizes in the correct amounts. It is synthetically derived and not made from the pineal glands of pigs. A synthetic melatonin ensures safety from viruses or other microbes that can be present in animal tissues. Pet Melatonin is also not a quick release or a slow acting form of melatonin. A simple form of melatonin is the ideal way to administer this supplement to a dog, and not quick or slow release. Pet Melatonin is enhanced with natural bacon flavor so it is something your dog will enjoy.

Milk Thistle

The liver performs dozens of different functions in the body, including clearing out toxins. Yet liver disease (including cirrhosis) is one of the most common health problems in older canines. It can damage all functions of the dog's liver, leading to very harmful health effects. Milk Thistle can help protect your pet against fatty liver, which is a risk if your pet suffers from Cushing's disease (due to elevated blood sugar levels).

Even canines without liver disease may need support to metabolize and excrete prescription medications, which are often damaging to the liver.

Milk Thistle should be administered to every dog taking liver-taxing medications and especially if the liver is damaged or diseased. Milk Thistle is not contradicted with conventional medications and is gentle enough for long term use.

Can my dog take Adrenal Harmony Gold, Melatonin and Milk Thistle with medications?

Do not give Adrenal Harmony Gold if your pet is taking blood-thinners. A veterinarian who has performed a complete medical check of your dog can help to establish safety of medications taken with other products or specific diets.

There are no studies showing adverse interactions between melatonin supplementation nor Milk Thistle with medications.

Does it come with a guarantee?

Yes!  Dr. Jan's Cushing's Kit comes with a 90-day, money-back guarantee.

Why choose this kit for your canine friend?

• Certified organic and ethically wild-harvested herbal ingredients:  Our formulas are entirely prepared from organically grown and ethically wild-harvested herbs.
• Good Manufacturing Practices:  All of our formulas are manufactured in a facility that adheres to Good Manufacturing Practices.
• Full Spectrum Extract:  The full biochemical spectrum of the herbs is preserved  to ensure the potency of the extract.  All raw materials are tested for identification and purity.
• Every batch tested:  Every batch of our Adrenal Harmony Gold is tested to ensure the highest quality and potency.  Every single batch.
• FDA-Registered Facility:  Our manufacturing facility is FDA-registered.  Strict quality control procedures are meticulously monitored.
• FDA Center for Veterinary Medicine Guidelines:  PetWellbeing.com complies with the provisions of the CVM's good guidance practices for pet dietary supplements.  All ingredients and caution statements adhere to these national guidelines.
• It's Guaranteed:  In addition to the superior quality of our products, you are also protected by our 90-day money-back guarantee.

Who makes Dr. Jan's Cushing's Kit for Dogs?

These products are made by PetWellbeing.com, founded in 2001.  Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet.  When your pet is healthy; you're happy.

To fulfill our vision, our on-staff, holistic veterinarians have developed formulas using time-honored, traditional uses of herbs, and integrated the latest scientific research.  It is our aim to produce the best products for your pet that we can.

Healthy Tip from Dr. Jan

Our Top Three Products for Dog Cushing's

This combination:

• Promotes healthy skin and coat
• Helps normal hair growth
• Supports normal thirst and urination
• Supports healthy weight and normal appetite
• Supports proper muscle tone
• Helps with anxiety and normal sleep patterns

A comment from our veterinarian

"As a veterinarian, it is challenging to treat this condition. I have noticed remarkable differences to dogs' quality of life when these three supplements are given daily. It's so nice to have something effective to offer my patients with Cushing's."

Description

Cushing's disease is the result of excessive levels of cortisol (a steroid hormone) in your dog's body for a long period of time. Cortisol is naturally produced by the adrenal glands that sit on top of the kidneys. During times of stress, or simply when more cortisol is needed, the hypothalamus and pituitary glands signal the adrenal glands to release more of the hormone into the body. There are three types of Cushing's disease that disrupt this process, and create a harmful level of cortisol in the body.

• Pituitary dependent - Affecting the majority of dogs with the disease, a tumor develops on the pituitary gland, signalling the adrenals to overproduce cortisol.
• Adrenal dependent - Much less frequently, a tumor may develop on one of the adrenal glands, directly leading to the overproduction of cortisol.
• Iatrogenic - After chronic use of corticosteroid drugs, used to treat other illnesses, Cushing's-like signs begin to develop.

How do you know if your dog is suffering from Cushing's? The disease is not very easy to diagnose, as cortisol levels fluctuate in the body at all times. A dog with Cushing's may exhibit these signs:

• Increased thirst and appetite
• Frequent urination
• Loss of hair
• Skin problems
• Panting
• Increased susceptibility to infections

Dr. Jan's Cushing's Kit for Dogs includes Adrenal Harmony Gold, Pet Melatonin, and Milk Thistle.

Adrenal Harmony Gold

This natural, liquid supplement was developed by our holistic veterinarians to support dogs with the physical manifestations of Cushing's. The therapeutic actions of the ingredients are: adaptogenic, antioxidant, and to give support to an overactive nervous system. These herbs are particularly suited to target the adrenal glands and their functions, but also exert an effect on the pituitary and hypothalamus glands.

"Adaptogens" are a classification of herbs considered to support the adrenals, helping the body adapt naturally to stressors and produce normal, healthy levels of cortisol. Unlike drugs, adaptogens will not stimulate or depress adrenal function, but instead they will help the glands normalize their production of hormones. As antioxidants, they will also combat oxidative (free radical) damage that can lead to degeneration.

Together, the ingredients in Adrenal Harmony Gold target key cellular mechanisms to help maintain normal balance.

Pet Melatonin

Melatonin is a naturally-occurring hormone produced in the pineal gland of dogs (and other animals), and plays a large role in regulating sleep patterns. It also has a role in the regulation of cortisol production.

In dogs, melatonin supplementation has been shown to target the adrenal cells and the amount of cortisol they make. This may support normal hair growth, normal appetite, and regular urination in dogs. It has been shown that having a consistent level of melatonin in the body can help support balanced cortisol output by the adrenal glands. Melatonin inhibits some of the enzymes needed for the body to produce more cortisol.

Pet Melatonin is different from the melatonin used for human consumption. Unlike capsules or tablets, its unique liquid form makes it ideal to administer to dogs of all sizes in the correct amounts. It is synthetically derived and not made from the pineal glands of pigs. A synthetic melatonin ensures safety from viruses or other microbes that can be present in animal tissues. Pet Melatonin is also not a quick release or a slow acting form of melatonin. A simple form of melatonin is the ideal way to administer this supplement to a dog, and not quick or slow release. Pet Melatonin is enhanced with natural bacon flavor so it is something your dog will enjoy.

Milk Thistle

The liver performs dozens of different functions in the body, including clearing out toxins. Yet liver disease (including cirrhosis) is one of the most common health problems in older canines. It can damage all functions of the dog's liver, leading to very harmful health effects. Milk Thistle can help protect your pet against fatty liver, which is a risk if your pet suffers from Cushing's disease (due to elevated blood sugar levels).

Even canines without liver disease may need support to metabolize and excrete prescription medications, which are often damaging to the liver.

Milk Thistle should be administered to every dog taking liver-taxing medications and especially if the liver is damaged or diseased. Milk Thistle is not contradicted with conventional medications and is gentle enough for long term use.

Can my dog take Adrenal Harmony Gold, Melatonin and Milk Thistle with medications?

Do not give Adrenal Harmony Gold if your pet is taking blood-thinners. A veterinarian who has performed a complete medical check of your dog can help to establish safety of medications taken with other products or specific diets.

There are no studies showing adverse interactions between melatonin supplementation nor Milk Thistle with medications.

Does it come with a guarantee?

Yes!  Dr. Jan's Cushing's Kit comes with a 90-day, money-back guarantee.

Why choose this kit for your canine friend?

• Certified organic and ethically wild-harvested herbal ingredients:  Our formulas are entirely prepared from organically grown and ethically wild-harvested herbs.
• Good Manufacturing Practices:  All of our formulas are manufactured in a facility that adheres to Good Manufacturing Practices.
• Full Spectrum Extract:  The full biochemical spectrum of the herbs is preserved  to ensure the potency of the extract.  All raw materials are tested for identification and purity.
• Every batch tested:  Every batch of our Adrenal Harmony Gold is tested to ensure the highest quality and potency.  Every single batch.
• FDA-Registered Facility:  Our manufacturing facility is FDA-registered.  Strict quality control procedures are meticulously monitored.
• FDA Center for Veterinary Medicine Guidelines:  PetWellbeing.com complies with the provisions of the CVM's good guidance practices for pet dietary supplements.  All ingredients and caution statements adhere to these national guidelines.
• It's Guaranteed:  In addition to the superior quality of our products, you are also protected by our 90-day money-back guarantee.

Who makes Dr. Jan's Cushing's Kit for Dogs?

These products are made by PetWellbeing.com, founded in 2001.  Our goal? To bring the wisdom and experience of our caring holistic veterinarians to your pet.  When your pet is healthy; you're happy.

To fulfill our vision, our on-staff, holistic veterinarians have developed formulas using time-honored, traditional uses of herbs, and integrated the latest scientific research.  It is our aim to produce the best products for your pet that we can.

Healthy Tip from Dr. Jan